BDBM362899 (S)-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-1-isopropyl-2-((-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)isoindoline-5-carboxamide Isomers::US9845308, Example 16a

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3[C@H](C(C)C)N(CC4CCC(OC4)C(F)(F)F)Cc3c2)nc1

InChI Key InChIKey=ZOBZUPDNBYRWRE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362899   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM362899(US9845308, Example 16a | (S)-N-((5-(ethylsulfonyl)...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent