BDBM363220 (R)-2-((2-(4-cyanobutoxy)-4-((2-methyl-[1,1′-biphenyl]-3-yl)methoxy)benzyl)amino)-3-hydroxypropanoic acid::US9850225, Example 1143

SMILES Cc1c(COc2ccc(CN[C@H](CO)C(O)=O)c(OCCCCC#N)c2)cccc1-c1ccccc1

InChI Key InChIKey=KCIPOQCKWMIDJI-HHHXNRCGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363220   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363220((R)-2-((2-(4-cyanobutoxy)-4-((2-methyl-[1,1′...)
Affinity DataIC50:  5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent