BDBM363228 5-((5-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzyloxy)-2-((2-hydroxyethylamino)methyl)-4-methylphenoxy)methyl)nicotinonitrile::US9850225, Example 1151

SMILES Cc1cc(CNCCO)c(OCc2cncc(c2)C#N)cc1OCc1cccc(c1Cl)-c1ccc2OCCOc2c1

InChI Key InChIKey=BFHUVOKFJFSOPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363228   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363228(5-((5-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]dioxin-...)
Affinity DataIC50:  5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent