BDBM363233 (R)-2-(4-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzyloxy)-2-((5-cyanopyridin-3-yl)methoxy)-5-methylbenzylamino)-3-hydroxy-2-methylpropanoic acid::US9850225, Example 1156

SMILES Cc1cc(CN[C@](C)(CO)C(O)=O)c(OCc2cncc(c2)C#N)cc1OCc1cccc(c1Cl)-c1ccc2OCCOc2c1

InChI Key InChIKey=DCMRPQIGXVSUNH-UUWRZZSWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363233   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363233((R)-2-(4-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]diox...)
Affinity DataIC50:  5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent