BDBM363433 (2S,5S)-1-(5-chloro-2-((5-cyanopyridin-3-yl)methoxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)benzyl)-5-hydroxypiperidine-2-carboxylic acid::US9850225, Example 2007
SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CN3C[C@@H](O)CC[C@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1
InChI Key InChIKey=ZLZSIDVOVQYDHW-IZEXYCQBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 363433
Affinity DataIC50: 5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair