BDBM365359 US10633373, Example 64::US10669265, Example 64::US9868726, Example 64::dimethyl {6-amino-5-[4-({[3- (trifluoromethyl)phenyl]carbamoyl} amino)phenyl]pyridin-3- yl}phosphonate

SMILES COP(=O)(OC)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=ANGIHPLFWQJTBG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 365359   

TargetPlatelet-derived growth factor receptor beta(Human)
Allergan

US Patent
LigandChemical structure of BindingDB Monomer ID 365359BDBM365359(US9868726, Example 64 | dimethyl {6-amino-5-[4-({[...)
Affinity DataIC50: 57nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandChemical structure of BindingDB Monomer ID 365359BDBM365359(US9868726, Example 64 | dimethyl {6-amino-5-[4-({[...)
Affinity DataIC50: 57nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandChemical structure of BindingDB Monomer ID 365359BDBM365359(US9868726, Example 64 | dimethyl {6-amino-5-[4-({[...)
Affinity DataIC50: 57nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent