BDBM36829 5-Phenyl-7-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[1,2,4]triazolo[1,5-a]pyrimidine::5-phenyl-7-[4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl]-[1,2,4]triazolo[1,5-a]pyrimidine::5-phenyl-7-[4-[5-(trifluoromethyl)-2-pyridyl]piperazino]-[1,2,4]triazolo[1,5-a]pyrimidine::5-phenyl-7-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-[1,2,4]triazolo[1,5-a]pyrimidine::MLS000035358::SMR000008093::cid_646427

SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC1)c1cc(nc2ncnn12)-c1ccccc1

InChI Key InChIKey=YYFIPTVPONYMFK-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 36829   

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36829(5-Phenyl-7-[4-(5-trifluoromethyl-pyridin-2-yl)-pip...)
Affinity DataEC50: >9.51E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36829(5-Phenyl-7-[4-(5-trifluoromethyl-pyridin-2-yl)-pip...)
Affinity DataEC50:  3.19E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36829(5-Phenyl-7-[4-(5-trifluoromethyl-pyridin-2-yl)-pip...)
Affinity DataEC50:  3.22E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein Wnt-3a(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM36829(5-Phenyl-7-[4-(5-trifluoromethyl-pyridin-2-yl)-pip...)
Affinity DataIC50:  5.78E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36829(5-Phenyl-7-[4-(5-trifluoromethyl-pyridin-2-yl)-pip...)
Affinity DataIC50:  2.12E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetZinc finger protein GLI1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM36829(5-Phenyl-7-[4-(5-trifluoromethyl-pyridin-2-yl)-pip...)
Affinity DataIC50:  3.60E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36829(5-Phenyl-7-[4-(5-trifluoromethyl-pyridin-2-yl)-pip...)
Affinity DataIC50:  1.06E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay