BDBM368758 N-[(1S)-1-[3-(difluoromethoxy)phenyl]ethyl]- 4-[6-(4-fluorophenyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]-2,2-dimethyl-piperazine-1- carboxamide::US10227357, Compound P-0006

SMILES Cc1c(C(=O)Nc2ccc([S@SP2](C)(=O)=O)c(F)c2)cn(CCO)c1-c1ccccc1C(F)(F)F

InChI Key InChIKey=JORITSIRSSPSJW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368758   

TargetMineralocorticoid receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 368758BDBM368758((S)-1-(2-Hydroxyethyl)-4-methyl-N-(3-fluoro-4-(met...)
Affinity DataIC50: 3.40nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent