BDBM368763 4-[4-(1H-benzimidazol-2-yl)piperazin-1-yl]-6- (4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine::US10227357, Compound P-0011

SMILES Cc1c(C(=O)Nc2cc(F)c3c(c2)sc(=O)n3C)cn(CCO)c1-c1ccccc1C(F)(F)F

InChI Key InChIKey=JRPOKDPREWNZIS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368763   

TargetMineralocorticoid receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 368763BDBM368763(N-(4-Fluoro-3-methyl-2-oxo-2,3-dihydrobenzo[d]thia...)
Affinity DataIC50: 82.2nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent