BDBM368834 4-[6-(3-sulfamoylphenyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]-N-[4- (trifluoromethoxy)phenyl]piperazine-1- carboxamide::US10227357, Compound P-0083

SMILES NS(=O)(=O)c1cccc(c1)-c1cc2c(ncnc2[nH]1)N1CCN(CC1)C(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=UFRKHCQQFZROCP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368834   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM368834(4-[6-(3-sulfamoylphenyl)-7H-pyrrolo[2,3- d]pyrimid...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM368834(4-[6-(3-sulfamoylphenyl)-7H-pyrrolo[2,3- d]pyrimid...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent