BDBM369022 N-[3-fluoro-4-(6-methyl-7H-pyrrolo[2,3- d]pyrimidin-4-yl)phenyl]-6-methyl- pyridine-3-sulfonamide::US10227357, Compound P-0286

SMILES O[C@H]1[C@H](O)CN(C[C@H]2CC[C@@H](C(F)(F)F)CC2)C[C@@H]1O

InChI Key InChIKey=VFWZTGONPHMZRV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369022   

TargetNon-lysosomal glucosylceramidase(Rat)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369022BDBM369022((3S,4R,5R)-1-(((1s,4S)-4-(trifluoromethyl)cyclohex...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent