BDBM369032 N-[4-[6-(cyclopenten-1-yl)-7H- pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]-4- fluoro-benzenesulfonamide::US10227357, Compound P-0296

SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1ncnc2[nH]c(cc12)C1=CCCC1

InChI Key InChIKey=MXCVXNHHJPBCIY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369032   

LigandPNGBDBM369032(US10227357, Compound P-0296 | N-[4-[6-(cyclopenten...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM369032(US10227357, Compound P-0296 | N-[4-[6-(cyclopenten...)
Affinity DataKi:  5.50E+3nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent