BDBM369116 N-[4-[4-[4- (cyclopropylsulfonylamino)phenyl]-7H- pyrrolo[2,3-d]pyrimidin-6- yl]phenyl]cyclopropanesulfonamide::US10227357, Compound P-0389

SMILES O[C@H]1[C@H](O)CN(CCc2c(F)cc(N3CCOCC3)cc2F)C[C@@H]1O

InChI Key InChIKey=RJUFZZZHPSIVFE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369116   

TargetNon-lysosomal glucosylceramidase(Rat)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369116BDBM369116((3S,4r,5R)-1-(2,6-difluoro-4-morpholinophenethyl)p...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent