BDBM369134 N-[2-fluoro-4-[6-(4-fluorophenyl)-7H- pyrrolo[2,3-d]pyrimidin-4- yl]phenyl]cyclopropanesulfonamide::US10227357, Compound P-0410

SMILES Cc1ncncc1N1CC[C@@H](CN2C[C@@H](O)[C@H](O)[C@@H](O)C2)C1

InChI Key InChIKey=ZXRHEUVLFCTZEW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369134   

TargetNon-lysosomal glucosylceramidase(Rat)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369134BDBM369134((3S,4S,5R)-1-(((S)-1-(4-(trifluoromethyl)pyrimidin...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent