BDBM369141 4-[6-(4-fluorophenyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]benzenesulfonamide::US10227357, Compound P-0418

SMILES O[C@H]1[C@H](O)CN(C[C@H]2CCCN(c3ncc(C(F)(F)F)s3)C2)C[C@@H]1O

InChI Key InChIKey=IOYGNRPOROYKIJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369141   

TargetNon-lysosomal glucosylceramidase(Rat)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369141BDBM369141((3S,4R,5R)-1-(((R)-1-(4-(trifluoromethyl)thiazol-2...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent