BDBM369172 5-methyl-N-[1-[6-(1-methylpyrazol-4- yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-4- piperidyl]benzothiophene-2- sulfonamide::US10227357, Compound P-0455

SMILES O[C@H]1[C@H](O)CN(C[C@H]2CC[C@H](OC(F)(F)F)CC2)C[C@@H]1O

InChI Key InChIKey=UVIRMPHCJJRHET-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369172   

TargetNon-lysosomal glucosylceramidase(Rat)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369172BDBM369172((3S,4R,5R)-1-(((1r,4R)-4-(trifluoromethoxy)cyclohe...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent