BDBM369176 N-[1-[6-(6-methyl-3-pyridyl)-7H- pyrrolo[2,3-d]pyrimidin-4-yl]-4- piperidyl]-4- (trifluoromethoxy)benzenesulfonamide::US10227357, Compound P-0459

SMILES Cc1ccccc1N1CCC(F)(CN2C[C@@H](O)[C@H](O)[C@@H](O)C2)CC1

InChI Key InChIKey=WZJXBHDACCMKMG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369176   

TargetNon-lysosomal glucosylceramidase(Rat)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369176BDBM369176((3S,4r,5R)-1-((4-fluoro-1-(2-(trifluoromethyl)phen...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent