BDBM369211 1-[1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)- 4-piperidyl]-3-[4- (trifluoromethyl)phenyl]urea::US10227357, Compound P-0514

SMILES O=C(Nc1ccc2c(c1)C(F)(F)C(=O)N2)c1coc2ccccc12

InChI Key InChIKey=JBPONLMJEJSYQF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369211   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369211BDBM369211(N-(3,3-Difluoro-1-oxo-indolin-5-yl)benzofuran-3-ca...)
Affinity DataKd:  52nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent