BDBM369253 3-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]-N-[(1S)-1-(3- methoxyphenyl)ethyl]-3,8- diazabicyclo[3.2.1]octane-8-carboxamide::US10227357, Compound P-0567

SMILES COc1cccc(c1)[C@H](C)NC(=O)N1C2CCC1CN(C2)c1ncnc2cc(sc12)-c1ccc(F)cc1

InChI Key InChIKey=FKJKEKKFAAAJHX-YTXWROIDSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369253   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM369253(3-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM369253(3-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]...)
Affinity DataKi:  1.05E+5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent