BDBM369388 4-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]-N-(2- thienylmethyl)piperazine-1-carboxamide::US10227357, Compound P-0709

SMILES Fc1ccc(cc1)-c1cc2ncnc(N3CCN(CC3)C(=O)NCc3cccs3)c2s1

InChI Key InChIKey=WCOWNLVZINMYHM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369388   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM369388(4-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM369388(4-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]...)
Affinity DataKi:  1.05E+5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent