BDBM369680 US10233156, Example I-220

SMILES C[C@@H](NC(C)=O)C(F)(F)C[C@H]1CC[C@@H](CO1)Oc1nc2c(F)cc(OCC(F)F)c(F)c2n1C

InChI Key InChIKey=UWEPAEJXEWUTAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 369680   

TargetAcetyl-CoA carboxylase 2(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 369680BDBM369680(US10233156, Example I-220 | US12521375, Compound I...)
Affinity DataIC50: 180nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 369680BDBM369680(US10233156, Example I-220 | US12521375, Compound I...)
Affinity DataIC50: 180nMAssay Description:Recombinant human ACC1 and recombinant human ACC2, which were prepared by the method mentioned above, were preincubated with assay buffer solution (5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 369680BDBM369680(US10233156, Example I-220 | US12521375, Compound I...)
Affinity DataIC50: 2.50E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details US Patent