BDBM369848 (R)—N-(1-(1-((1-Acetylazetidin-3-yl)methyl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-2-fluoro-5-(trifluoromethyl)benzamide::US10233182, Example 121

SMILES CC(C)[C@@H](NC(=O)c1cc(ccc1F)C(F)(F)F)C(=O)N1CCC2(CC1)N(CC1CN(C1)C(C)=O)C(=O)N(C)C2=O

InChI Key InChIKey=MBAPDORGNGYDFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369848   

TargetAutotaxin(Human)
X-Rx

US Patent
LigandChemical structure of BindingDB Monomer ID 369848BDBM369848(US10233182, Example 121 | (R)—N-(1-(1-((1-Ace...)
Affinity DataIC50: 1.00E+3nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent