BDBM370271 BDBM467166::US10233188, Example 158

SMILES COCCc1cc2cnc(N[C@H]3CCN(C[C@@H]3F)S(C)(=O)=O)nc2n(C2CCCC2)c1=O

InChI Key InChIKey=FTCGQLTXUPUONY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 370271   

LigandPNGBDBM370271(BDBM467166 | US10233188, Example 158)
Affinity DataKi:  0.660nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370271(BDBM467166 | US10233188, Example 158)
Affinity DataKi:  0.660nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

LigandPNGBDBM370271(BDBM467166 | US10233188, Example 158)
Affinity DataKi:  0.660nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

LigandPNGBDBM370271(BDBM467166 | US10233188, Example 158)
Affinity DataKi:  3.89nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

LigandPNGBDBM370271(BDBM467166 | US10233188, Example 158)
Affinity DataKi:  3.89nMAssay Description:The mobility shift assay electrophoretically separates the fluorescently labeled peptides (substrate and phosphorylated product) following the kinase...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370271(BDBM467166 | US10233188, Example 158)
Affinity DataKi:  3.89nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent