BDBM3709 4-N-(3-bromophenyl)-6-N-[2-(dimethylamino)ethyl]-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Bromophenyl)amino]-6-[N-[2-(dimethylamino)-ethyl]-N-methylamino]pyrido[3,4-d]pyrimidine::PD158780 Analog 5m

SMILES CN(C)CCN(C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1

InChI Key InChIKey=HTUBDSNBHLULPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3709   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3709(4-N-(3-bromophenyl)-6-N-[2-(dimethylamino)ethyl]-6...)
Affinity DataIC50: 8.10nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed