BDBM371914 US10239870, Example 140::US10239870, Example 141

SMILES Cn1c(SCCCN2CC[C@]3(CC3c3ccc(cc3)C(F)(F)F)C2)nnc1-c1ccccn1

InChI Key InChIKey=BGJXBVUWLFEJNM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 371914   

TargetD(3) dopamine receptor(Rat)
Indivior

US Patent
LigandPNGBDBM371914(US10239870, Example 141 | US10239870, Example 140)
Affinity DataKi:  0.794nMAssay Description:[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Indivior

US Patent
LigandPNGBDBM371914(US10239870, Example 141 | US10239870, Example 140)
Affinity DataKi:  7.76nMAssay Description:[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Indivior

US Patent
LigandPNGBDBM371914(US10239870, Example 141 | US10239870, Example 140)
Affinity DataKi:  107nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were seeded into b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Indivior

US Patent
LigandPNGBDBM371914(US10239870, Example 141 | US10239870, Example 140)
Affinity DataKi:  525nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were re-suspended ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Indivior

US Patent
LigandPNGBDBM371914(US10239870, Example 141 | US10239870, Example 140)
Affinity DataKi:  631nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were re-suspended ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent