BDBM372267 3,4-dimethyl-N-(1-(5- (trifluoromethyl) pyrimidin-2-yl)azetidin- 3-yl)pyrimido[4',5':4,5] thieno[2,3-c]pyridazin-8- amine::US10239887, Cpd. No. 7

SMILES O=C(O)[C@H]1CCC[C@H]1C(=O)N[C@@H](c1ccccc1)c1ccc(C2CCC2)cn1

InChI Key InChIKey=NGCMHJVOEXCXKY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372267   

TargetGlycogen [starch] synthase, muscle/Glycogenin-1 (GN1)(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 372267BDBM372267(US20260021085, Compound 15)
Affinity DataIC50: 497nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetGlycogen [starch] synthase, liver/Glycogenin-1 (GN1)(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 372267BDBM372267(US20260021085, Compound 15)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent