BDBM372270 8-(3-azabicyclo[3.1.0] hexan-3-yl)-3,4- dimethylpyrimido [4',5':4,5]thieno[2,3-c] pyridazine::US10239887, Cpd. No. 10

SMILES O=C(O)[C@H]1CCC[C@H]1C(=O)N[C@@H](c1ccccc1)c1ccc(C2CCC2)c(F)c1

InChI Key InChIKey=LJNYDIGNZVYAHL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372270   

TargetGlycogen [starch] synthase, muscle/Glycogenin-1 (GN1)(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 372270BDBM372270(US20260021085, Compound 18)
Affinity DataIC50: 384nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetGlycogen [starch] synthase, liver/Glycogenin-1 (GN1)(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 372270BDBM372270(US20260021085, Compound 18)
Affinity DataIC50: 2.86E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent