BDBM372275 8-methyl-4- (pyrrolidin-1-yl) pyrido[3',2':4,5]thieno [3,2-d]pyrimidine::US10239887, Cpd. No. 15

SMILES Cc1ccccc1[C@H](NC(=O)[C@@H]1CCC[C@@H]1C(=O)O)c1ccc(C(C)C)c(F)c1

InChI Key InChIKey=WNVHONNDYZZMQU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372275   

TargetGlycogen [starch] synthase, muscle/Glycogenin-1 (GN1)(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 372275BDBM372275(Synthesis of (1S,2R)-2-(((R)-(3-fluoro-4-isopropyl...)
Affinity DataIC50: 166nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetGlycogen [starch] synthase, liver/Glycogenin-1 (GN1)(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 372275BDBM372275(Synthesis of (1S,2R)-2-(((R)-(3-fluoro-4-isopropyl...)
Affinity DataIC50: 8.48E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent