BDBM373138 US9896452, Example 3::rac-(5-Fluoro-2-((5-(trifluoromethyl)pyridin-2-ylamino)methyl)piperidin-1-yl)(2-methyl-5-phenylthiazol-4-yl)methanone

SMILES C#Cc1c(F)ccc2cc(O)cc(-c3ncc4c([C@H]5[C@@H]6CNC[C@@H]65)nn(CC)c4c3F)c12

InChI Key InChIKey=GJDYBOVHDFWUGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373138   

TargetGTPase NRas [G12D](Human)
University of Texas System

US Patent
LigandChemical structure of BindingDB Monomer ID 373138BDBM373138(4-(3-((1R,5S,6r)-3-azabicyclo[3.1.0]hexan-6- yl)-1...)
Affinity DataKd:  159nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent