BDBM373154 US9896452, Example 16::rac-((2S,3R)-2-(((5-ethylpyrimidin-2-yl)amino)methyl)-3-methylpiperidin-1-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanone

SMILES C#Cc1c(F)ccc2cc(O)cc(-c3c(F)cc4c([C@H]5[C@@H]6CNC[C@@H]65)cn(C)c4c3F)c12

InChI Key InChIKey=UWCLPLRBLDMNBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373154   

TargetGTPase NRas [G12D](Human)
University of Texas System

US Patent
LigandChemical structure of BindingDB Monomer ID 373154BDBM373154(4-(3-((1R,5S,6s)-3-azabicyclo[3.1.0]hexan-6- yl)-5...)
Affinity DataKd:  965nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent