BDBM373199 US9896452, Example 59::rac-N-((1-(5-(4-fluorophenyl)-2-methylthiazole-4-carbonyl)-6-methylpiperidin-2-yl)methyl)quinoline-8-carboxamide

SMILES C#Cc1c(F)ccc2cc(O)cc(-c3ncc4c([C@H]5[C@@H]6CNC(CO)[C@@H]65)nn(C)c4c3F)c12

InChI Key InChIKey=QDFUSTLNIXAUHP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373199   

TargetGTPase NRas [G12D](Human)
University of Texas System

US Patent
LigandChemical structure of BindingDB Monomer ID 373199BDBM373199(5-ethynyl-6-fluoro-4-(7-fluoro-3-((1S,5R,6S)-2- (h...)
Affinity DataKd:  190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent