BDBM373239 US9896452, Example 102::rac-(1-((benzo[d]oxazol-2-yloxy)methyl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanone

SMILES CCOC(=O)c1ccc2oc(-c3ccc(CNC(=O)c4cnc5nccn5c4)cc3)nc2c1

InChI Key InChIKey=UQSGROBTFODQKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373239   

TargetNicotinamide phosphoribosyltransferase(Human)
Checkmate Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 373239BDBM373239(US20260022122, Example 29)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent