BDBM373264 N-(((2S,4S)-1-([1,1′-biphenyl]-2-carbonyl)-4-methoxypyrrolidin-2-yl)methyl)quinoline-8-carboxamide::US9896452, Example 127

SMILES COc1cc2nc(-c3ccc(CNC(=O)c4cnc5nccn5c4)cc3)oc2cc1C

InChI Key InChIKey=LCUULBNNTBGAPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373264   

TargetNicotinamide phosphoribosyltransferase(Human)
Checkmate Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 373264BDBM373264(US20260022122, Example 43)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent