BDBM373277 US9896452, Example 141::rac-N-(((1s,4s)-2-(2-methyl-5-phenylthiazole-4-carbonyl)-2-azabicyclo[2.2.2]octan-3-yl)methyl)quinoline-8-carboxamide

SMILES O=C(NCc1ccc(-c2nc3cc(Cl)ccc3s2)cc1)c1cnc2nccn2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373277   

TargetNicotinamide phosphoribosyltransferase(Human)
Checkmate Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 373277BDBM373277(US20260022122, Example 49)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent