BDBM373352 ((2S,3R)-3-Methyl-2-(((5-(trifluoromethyl)pyridin-2-yl)amino)methyl)piperidin-1-yl)(5-methyl-2-(3-methyl-1H-pyrazol-1-yl)phenyl)methanone::US9896452, Ex. A108

SMILES CO[C@@H]1CCN(C(=O)c2cn3nccc(Oc4ccc5[nH]c(C)cc5c4F)c3c2C)C1

InChI Key InChIKey=MZHLVUVPAFKQLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373352   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 373352BDBM373352({4-[(4-fluoro-2-methyl-1H- indol-5-yl)oxy]-5- meth...)
Affinity DataEC50:  1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent