BDBM373377 ((2S,3R)-3-Methyl-2-(((5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)amino)methyl)piperidin-1-yl)(5-methyl-2-(4-methyl-2H-1,2,3-triazol-2-yl)phenyl)methanone::US9896452, Ex. A135

SMILES CNC(=O)n5c(C)cc4cc(Oc2ccnn3cc(C(=O)N1C[C@@](C)(O)[C@H]1C)c(C)c23)ccc45

InChI Key InChIKey=VVGRATQGRFCDNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373377   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 373377BDBM373377(6-((6-((1R,4R)-2-oxa-5- azabicyclo[2.2.1]heptane-5...)
Affinity DataEC50:  1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent