BDBM373393 ((2S,3R)-3-Methyl-2-(((5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)amino)methyl)piperidin-1-yl)(5-methyl-2-(pyridin-2-yl)phenyl)methanone::US9896452, Ex. A151

SMILES CNC(=O)c1c(C)oc2cc(Oc3ccnn4cc(C(=O)N5C[C@H](O)[C@H]5C)c(C)c34)ccc12

InChI Key InChIKey=MBXXWRKSWWCYFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373393   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 373393BDBM373393(6-({6-[(2R,3S)-3-hydroxy-2- methylazetidine-1-carb...)
Affinity DataEC50:  0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent