BDBM373467 ((2S,3R)-2-(((5-Chloropyridin-2-yl)amino)methyl)-3-methylpiperidin-1-yl)(5-fluoro-2-(pyrimidin-2-yl)phenyl)methanone::US9896452, Ex. A229

SMILES Cc1oc2cc(Oc3ccnn4cc(C(=O)N5C[C@H](F)[C@H]5C)c(C)c34)ccc2c1C(=O)NCC1CC1

InChI Key InChIKey=GDIBHJFPOZOJID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373467   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 373467BDBM373467(N-(cyclopropylmethyl)-6-({6- [(2R,3S)-3-fluoro-2- ...)
Affinity DataEC50:  1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent