BDBM380113 4-oxo-N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-5-(propan-2- yl)-3H,4H-pyrrolo[2,1- f][1,2,4]triazine-6- carboxamide::US9926282, Example 108
SMILES CC(C)c1c(cn2nc[nH]c(=O)c12)C(=O)Nc1ccc(cc1)-c1n[nH]c(=O)c2ccccc12
InChI Key InChIKey=MGVBGLCUYUWDBS-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 380113
Affinity DataIC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair