BDBM380548 6-methyl-N-((1R,4R)-4-(3-(methylsulfonyl)azetidin-1-yl)cyclohexyl)quinazolin-4-amine::US9926330, 2-1

SMILES Cc1ccc2ncnc(NC3CC[C@@H](CC3)N3CC(C3)S(C)(=O)=O)c2c1

InChI Key InChIKey=OEVWBLYSJKFBNL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380548   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380548(US9926330, 2-1 | 6-methyl-N-((1R,4R)-4-(3-(methyls...)
Affinity DataIC50: 384nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent