BDBM380591 1-(4-{[trans-4- (dimethylamino)cyclo- hexyl]amino}quinazolin- 6-yl)ethanol::US9926330, 5-4

SMILES CC(O)c1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N(C)C)c2c1

InChI Key InChIKey=DTLWRNBGXWZTBG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380591   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380591(US9926330, 5-4 | 1-(4-{[trans-4- (dimethylamino)cy...)
Affinity DataIC50: 29nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent