BDBM380803 2-Chloro-4-(4-hydroxy-3,4-dihydro- 1H-pyrano[4,3-c]pyridin-8-yl)- benzonitrile, Enantiomer I::US9890171, 7

SMILES OC1COCc2c1cncc2-c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=CRYBMHQRFCECPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380803   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380803(2-Chloro-4-(4-hydroxy-3,4-dihydro- 1H-pyrano[4,3-c...)
Affinity DataIC50: 6.10nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent