BDBM380810 8-(3-Methyl-3H-benzotriazol-5-yl)- 3,4-dihydro-1H- pyrano[4,3-c]pyridin-4-ol, Enantiomer II::US9890171, 14::US9890171, 188

SMILES Cn1nnc2ccc(cc12)-c1cncc2C(O)COCc12

InChI Key InChIKey=VFJBQDXZYXOGCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 380810   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380810(US9890171, 188 | 8-(3-Methyl-3H-benzotriazol-5-yl)...)
Affinity DataIC50: 15.7nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380810(US9890171, 188 | 8-(3-Methyl-3H-benzotriazol-5-yl)...)
Affinity DataIC50: 21nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent