BDBM380892 8-(4-Fluoro-1-methyl-1H-indazol-6- yl)-3,4-dihydro-1H-pyrano[4,3- c]pyridin-4-ol, Enantiomer II::US9890171, 96

SMILES Cn1ncc2c(F)cc(cc12)-c1cncc2C(O)COCc12

InChI Key InChIKey=JYRMIZIVSXMZQL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380892   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380892(8-(4-Fluoro-1-methyl-1H-indazol-6- yl)-3,4-dihydro...)
Affinity DataIC50: 8.10nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent