BDBM380910 8-(3-methyl-1,2-benzoxazol-5- yl)spiro[1,4-dihydropyrano[4,3- c]pyridine-3,1'-cyclopropane]-4-ol, Enantiomer II::US9890171, 114

SMILES Cc1noc2ccc(cc12)-c1cncc2C(O)C3(CC3)OCc12

InChI Key InChIKey=KNANUVNBSWBJRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380910   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380910(8-(3-methyl-1,2-benzoxazol-5- yl)spiro[1,4-dihydro...)
Affinity DataIC50: 18.8nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent