BDBM380983 8-(1-Methyl-4,5-dihydro-1H-indazol- 6-yl)-3,4-dihydro-1H-pyrano[4,3- c]pyridin-4-ol, Enantiomer II::US9890171, 187::US9890171, 189

SMILES Cn1ncc2CCC(=Cc12)c1cncc2C(O)COCc12

InChI Key InChIKey=PVDWAAJKGDKQAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 380983   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380983(US9890171, 189 | 8-(1-Methyl-4,5-dihydro-1H-indazo...)
Affinity DataIC50: 12.9nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380983(US9890171, 189 | 8-(1-Methyl-4,5-dihydro-1H-indazo...)
Affinity DataIC50: 67nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent