BDBM380993 8-(3-methylbenzotriazol-5- yl)spiro[1,4-dihydropyrano[4,3- c]pyridine-3,1''-cyclopropane]-4-ol, Enantiomer I::US9890171, 197::US9890171, 198

SMILES Cn1nnc2ccc(cc12)-c1cncc2C(O)C3(CC3)OCc12

InChI Key InChIKey=JQQOITKEBIBSKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 380993   

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380993(US9890171, 198 | 8-(3-methylbenzotriazol-5- yl)spi...)
Affinity DataIC50: 18nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380993(US9890171, 198 | 8-(3-methylbenzotriazol-5- yl)spi...)
Affinity DataIC50: 19nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent