BDBM382063 2-[1-(cyclopropylmethyl)-5-(4- fluorophenyl)imidazol-4- yl]pyridine-4-carboxylic acid::US10273222, Example 125

SMILES OC(=O)c1ccnc(c1)-c1ncn(CC2CC2)c1-c1ccc(F)cc1

InChI Key InChIKey=CRVQLJOEUPYQFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382063   

TargetLysine-specific demethylase 2B(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382063BDBM382063(2-[1-(cyclopropylmethyl)-5-(4- fluorophenyl)imidaz...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382063BDBM382063(2-[1-(cyclopropylmethyl)-5-(4- fluorophenyl)imidaz...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent