BDBM382070 2-[1-[2-(2-chlorophenyl)ethyl]-5- (4-fluorophenyl)imidazol-4-yl]-4- (2H-tetrazol-5-yl)pyridine::US10273222, Example 132

SMILES Fc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2CCc2ccccc2Cl)cc1

InChI Key InChIKey=HQHTWKLZEQTHKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382070   

TargetLysine-specific demethylase 2B(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382070BDBM382070(2-[1-[2-(2-chlorophenyl)ethyl]-5- (4-fluorophenyl)...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382070BDBM382070(2-[1-[2-(2-chlorophenyl)ethyl]-5- (4-fluorophenyl)...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent