BDBM382081 2-[1-(1,2,3,4- tetrahydronaphthalen-1- ylmethyl)imidazol-4-yl]-4-(2H- tetrazol-5-yl)pyridine::US10273222, Example 143

SMILES c1ccc2c(c1)CCCC2Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1

InChI Key InChIKey=AHJAGGVQXVXBBG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 382081   

TargetLysine-specific demethylase 2B(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382081BDBM382081(2-[1-(1,2,3,4- tetrahydronaphthalen-1- ylmethyl)im...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382081BDBM382081(2-[1-(1,2,3,4- tetrahydronaphthalen-1- ylmethyl)im...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382081BDBM382081(2-[1-(1,2,3,4- tetrahydronaphthalen-1- ylmethyl)im...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4A(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382081BDBM382081(2-[1-(1,2,3,4- tetrahydronaphthalen-1- ylmethyl)im...)
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent